Sara Yazdani

My research lies at the intersection of biotechnology, materials science, and physical chemistry, focusing on advancing drug delivery systems, gene therapy, and biomaterials. A key area of interest is biocompatible nanocarriers’ synthesis and surface modification to optimize their functionality, safety, and efficacy. My work includes the design of innovative biomaterials for targeted and controlled drug delivery, emphasizing improving the stability, solubility, and interaction of therapeutic agents with biological systems.

I have a particular interest in developing nanostructures designed for gene therapy, enabling the efficient and safe delivery of genetic materials such as DNA and RNA. My research also involves studying surface chemistry and functionalization techniques, including covalent and non-covalent modifications, to enhance the biocompatibility and targeted delivery capabilities of nanocarriers.

Additionally, I explore the application of protein-based nanoparticles in drug and gene delivery, tissue engineering, and vaccine development. My expertise includes utilizing advanced characterization methods to evaluate nanocarrier morphology, surface charge, and release kinetics, along with employing molecular dynamics simulations and thermodynamic analyses to understand nanocarrier-drug interactions.

Through an integrative and multidisciplinary approach, my research seeks to overcome biological barriers such as the cell membrane, blood-brain barrier, and immune system responses, thereby addressing critical challenges in human health. By harnessing the potential of nanomedicine and precision engineering, my goal is to develop transformative therapies to advance need-based medicine and improve patient outcomes.